Nanotechnology holds the potential to enable a new generation of high-density, multianalyte sensors to fill the rising demand for highly selective, highly sensitive smart sensor systems capable of simultaneously detecting multiple species. Organizers of this NNI workshop chose to focus on nanotechnology-enabled signal transducers and the insertion of these sensing elements into sensor systems.

This report on Regional, State, and Local (RSL) Initiatives in Nanotechnology is the result of a topical workshop convened 1–3 April 2009 in Oklahoma City, Oklahoma, by the Nanoscale Science, Engineering, and Technology (NSET) Subcommittee of the National Science and Technology Council’s Committee on Technology.

This workshop was the first in a series of four workshops sponsored by the NSET Subcommittee to inform the NNI’s long-range planning efforts for environmental, health, and safety research.