Nanoscale bumps and grooves trigger big changes in cell behavior

Date posted
Funding Agency
(Funded by the National Science Foundation, the U.S. Department of Defense, and the National Institutes of Health)

Researchers at the University of California San Diego have developed a platform for studying how  nanoscale growing surfaces can impact cellular behavior. While previous studies have shown how surface structures can change cellular shape, little is known about their specific effects on cell metabolism. The research team found that cells grown on engineered nanopillar surfaces show dramatically different metabolic profiles than cells not grown on such surfaces. Also, the researchers found that growing cells on different engineered nanopillar surfaces could change how cells produce and modify lipids, the primary components of cell membranes.