The Department of the Treasury (DOTreas) works through the NSET Subcommittee to help the NNI achieve its vision congruent with the DOTreas: to serve the American people and strengthen national security by managing the U.S. Federal Government’s finances effectively, to promote economic growth and stability, and to ensure the safety, soundness, and security of U.S. and international financial systems. DOTreas monitors those aspects of developing nanotechnology that could most effectively assist the execution of its role as the steward of the U.S. economic and financial systems, and as an influential participant in the global economy. DOTreas seeks to assess and utilize nanotechnology in the discharge of its responsibilities, including advising the President on economic and financial issues, encouraging sustainable economic growth, and fostering improved governance in financial institutions. It seeks to harness those aspects of nanotechnology R&D that will allow it to better operate and maintain systems that are critical to the nation’s financial infrastructure, such as the production of coin and currency. Interactions with the NSET Subcommittee help DOTreas as it endeavors to capture developments in nanoscale science and engineering that are changing the parameters of its domestic and international operations, particularly those impacting its critical national security-related activities in implementing economic sanctions against foreign threats to the United States, identifying and targeting the financial support networks of national security threats, improving the safeguards of U.S. financial systems, and creating new economic and job opportunities to promote economic growth and stability at home and abroad.