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(Funded by the National Institutes of Health and the National Science Foundation)
A collaboration of Duke University engineers and immunologists have developed a method to test DNA bound to nanoparticles in the bloodstream. These complexes have been linked to autoimmune diseases such as systemic lupus erythematosus (lupus). The study found that DNA adsorbed on the surface of polystyrene nanoparticles was resistant to degradation. These findings advance understanding of the inflammatory response to DNA on particle surfaces in immune-mediated diseases.
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