Accelerating CAR T cell therapy: Lipid nanoparticles speed up manufacturing

Engineers at the University of Pennsylvania have developed a novel method for manufacturing chimeric antigen receptor (CAR) T cells, specialized receptors that help T cells eliminate cancer cells. The researchers used lipid nanoparticles (LNPs) to activate T cells and deliver the genetic instructions for CARs in a single step, simplifying the CAR T cell manufacturing process. LNPs are being used as delivery vehicles in vaccine and other biomedical developments.