Researchers develop puffed-up MOFs for improved drug delivery

Researchers from the University of Miami, Missouri University of Science and Technology, and Cleveland State University have treated a chromium-containing nanoscale metal-organic framework to expand its pore size and surface area. The puffed-up metal-organic framework, created by the addition of concentrated acetic acid, held more ibuprofen or a chemotherapy drug than the original version and showed improved performance as a potential drug-delivery vehicle.