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(Funded by the National Institutes of Health and the U.S. Department of Defense)
By folding DNA into a virus-like structure, researchers at MIT have designed HIV-like nanoparticles that provoke a strong immune response from human immune cells grown in a lab dish. The DNA nanoparticles, which closely mimic the size and shape of HIV viruses, are coated with HIV proteins that are arranged in precise patterns designed to provoke a strong immune response. Such nanoparticles might eventually be used as an HIV vaccine.
