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(Funded by the National Institutes of Health)
Researchers at the Perelman School of Medicine at the University of Pennsylvania have found that a type of vaccine called a nucleoside-modified mRNA encapsulated in lipid nanoparticles (mRNA-LNP) vaccine, which was developed at Penn, successfully protected young mice against infections in the presence of maternal antibodies. The study suggests that this protection occurred because the vaccine programs cells to constantly churn out new antigens for a prolonged period of time, rather than delivering a one-time shot of a viral protein.
