Little Size Holds Big Impact: Johns Hopkins Scientists Develop Nanocontainer to Ship Titan-Size Gene Therapies and Drugs into Cells

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Funding Agency
(Funded by the National Science Foundation and the National Institutes of Health)

Scientists at Johns Hopkins Medicine report that they have created a tiny, nano-size container that can slip inside cells and deliver protein-based medicines and gene therapies of any size — even hefty ones attached to a gene-editing tool called CRISPR. If their creation — constructed of a biodegradable polymer — passes more laboratory testing, it could offer a way to efficiently ferry larger medical compounds into specifically selected target cells.