Biomaterials smarten up with CRISPR

Date posted
Funding Agency
(Funded by the Defense Threat Reduction Agency)

A research team at Harvard's Wyss Institute for Biologically Inspired Engineering and the Massachusetts Institute of Technology demonstrates the use of CRISPR as a control element in a new type of stimuli-responsive "smart" materials. Upon activation by DNA stimuli, a CRISPR-Cas enzyme enables smart materials to release fluorescent dyes and active enzymes, deploy encapsulated nanoparticles and live cells, or regulate electric circuits.