Vaccine design can dramatically improve cancer immunotherapies

Date posted
Funding Agency
(Funded by the National Institutes of Health and the Office of Naval Research)

Researchers have investigated a set of spherical nucleic acids (SNAs) for their potential to stimulate cancer-quelling immune responses. After comparing compositionally identical yet structurally different vaccines, the researchers found the structure of SNAs in one vaccine dramatically outperformed the others. Vaccines with the superior structure eliminated tumors in 30% of animals and improved their overall survival from cancer.