Scientists use nanoparticle-delivered gene-therapy to inhibit blinding eye disease in rodents

Date posted
Funding Agency
(Funded by the National Institutes of Health)

In experiments in rats and mice, two researchers from Johns Hopkins University have reported the successful use of nanoparticles to deliver gene therapy for wet age-related macular degeneration – an eye disease characterized by abnormal blood vessel growth that damages the light-sensitive tissue in the back of the eye. The research provides evidence of the potential value of nanoparticle-delivered gene therapy to treat wet age-related macular degeneration as well as rare, inherited blinding diseases of the retina.