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(Funded by the National Institutes of Health and the National Science Foundation)
A team led by researchers at the Georgia Institute of Technology has cultured the human blood-brain barrier on a chip, re-creating its physiology more realistically than predecessor chips. In testing related to drug delivery, nanoparticles moved through this “blood-brain-barrier-on-a-chip” after engaging endothelial cell receptors, which caused these cells to engulf the nanoparticles and then transport them to what would be inside the human brain in a natural setting.
